Pemphigus vegetans = الفقاع المتنبت |
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Pemphigus Vegetans
Pemphigus vegetans is an uncommon variant of pemphigus vulgaris, comprising only 1 % to 2% of cases . Historically, pemphigus vegetans has been divided into the Neumann type and Hallopeau type. In the more severe Neumann type, the disease begins and ends as pemphigus vulgaris, but many of the denuded areas heal with verrucous vegetations that may contain small pustules in early stages. The Hallopeau type is relatively benign, having pustules as the primary lesions instead of bullae. Their development is followed by the formation of gradually enlarging verrucous vegetations, especially in intertriginous areas.
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Histopathology.
In the Neumann type, the early lesions consist of bullae and denuded areas that have the same histologic picture as that of pemphigus vulgaris. As the lesions age, however, there is formation of villi and verrucous epidermal hyperplasia. Numerous eosinophils are present within the epidermis and dermis
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