SYRINGOMA
Epidemiology.
Common. Adult women are most commonly affected, but these can occur in all adults.
Etiology.
Syringoma is a benign neoplasm with differentiation toward eccrine acrosyringium.
Clinical Findings.
Syringomas present as numerous, small, firm, smooth, skin-colored, or slightly yellowish papules situated on the face, particularly around the lower eyelids of adults, but can develop in other anatomic sites. Women are more commonly affected. Scalp lesions often present as non-scarring alopecia. Syringomas occasionally show a unilateral, linear, or bathing trunk-type distribution. Familial cases have been recorded. There appears to be an increased frequency of syringomas in patients with Down syndrome. Eruptive syringomas represent a distinctive, occasionally familial form presenting mainly in pubescent or adolescent girls as successive crops of numerous, disseminated, sometimes confluent papules. These lesions tend to involve the upper half of the body, particularly the anterior aspect of the neck, chest, trunk, axillae, inner aspects of the upper arms, and umbilical area.
Histopathology.
Numerous epithelial aggregations of small, tadpole-shaped solid nests, cords, and tubular structures in the upper half of the dermis . The epithelial areas are commonly surrounded by thickened, closely packed, collagen bundles.
Treatment.
Some patients seek removal of the lesions because of cosmetic concerns. Surgical excision generally produces less than satisfactory cosmetic results. Alternative therapeutic approaches may include dermabrasion, electrodesiccation with curettage, and laser resurfacing