Woolly_hair = الشعر الصوفي |
WOOLLY HAIR
Woolly hair is the presence of kinky, wavy hair on the scalp of persons of non-African or Negroid background. Microscopically, the hairs are tightly coiled. The unruly hair presents at birth or in infancy, usually as a solitary problem inherited in an autosomal dominant fashion. Mutations in the genes for the desmosomal proteins plakoglobin (Naxos disease) or desmoplakin give rise to the triad of woolly hair, striate palmar-plantar keratoderma, and cardiomyopathy. Both recessive and dominant patterns of inheritance have been reported. Assessment of cardiac status should be performed in all children presenting with generalized woolly hair. A sporadic variant has been reported with fine, white-blond hair . Diffuse partial woolly hair, a recently described autosomal dominant condition, presents in young adulthood with two distinct populations of scalp hair, one straight and the other very curly. The curly hairs are thinner than normal hairs, which may contribute to the clinical appearance of a reduction in hair density. Woolly hair may also occur in a localized form (see Woolly Hair Nevus under Primary or Acquired Hair Shaft Abnormalities).
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