Geographic tongue = اللسان الجغرافي |
Geographic Tongue Geographic tongue (benign migratory glossitis) is a benign condition that occurs in up to 3% of the general population. Most often, patients are asymptomatic; however, some patients report increased sensitivity to hot and spicy foods. The etiology and pathogenesis of geographic tongue are still poorly understood. Geographic tongue affects males and females and is noted to be more prominent in adults than in children.1,2 The classic manifestation of geographic tongue is an area of erythema, with atrophy of the filiform papillae of the tongue, surrounded by a serpiginous, white, hyperkeratotic border. The patient often reports spontaneous resolution of the lesion in one area, with the return of normal tongue architecture, only to have another lesion appear in a different location of the tongue. Lesion activity in geographic tongue may wax and wane over time, and patients are occasionally free of lesions. If lesions occur at other mucosal sites, the condition is termed erythema migrans. The most commonly affected site is the tongue; however, other oral mucosal soft tissue sites may be affected. Geographic tongue has been reported with increased frequency in patients with psoriasis3,4,5,6,7 and in patients with fissured tongue.8,9 Although geographic tongue is an inflammatory condition histologically, a polygenic mode of inheritance has been suggested because it is seen clustering in families. Associations with human leukocyte antigen (HLA)–DR5, HLA-DRW6, and HLA-Cw6 have also been reported.10,11 Geographic tongue has reportedly occurred in up to 3% of the general population in the United States. International frequency rates for geographic tongue are similar to those reported in the United States. Geographic tongue is a benign condition. No racial or ethnic predilection is reported for geographic tongue. Females have been reported to be affected twice as often as males.12 Exacerbations have been suggested to be related to hormonal factors. Geographic tongue can affect all age groups; however, it is more predominant in adults than in children.
No increased incidence of geographic tongue has been noted with medication use or environmental agents
Treatment No medical intervention is required because the lesion is benign and most often asymptomatic. However, Abe et al report successful treatment with cyclosporin,17 and Sigal and Mock reported treatment with topical and systemic antihistamines.18 Consultation with an oral pathologist is indicated if a question exists about the diagnosis.
|